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US Patent 7687516 Alcohol free formulation of argatroban

Patent 7687516 was granted and assigned to Eagle Pharmaceuticals, Inc. on March, 2010 by the United States Patent and Trademark Office.

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Patent

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Current Assignee
Eagle Pharmaceuticals, Inc.
Eagle Pharmaceuticals, Inc.
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7687516
Patent Inventor Names
Nageswara R. Palepu0
Date of Patent
March 30, 2010
Patent Application Number
11973485
Date Filed
October 9, 2007
Patent Primary Examiner
‌
David J Blanchard
Patent abstract

An aqueous formulation of argatroban and of related compounds is disclosed along with a reconstitutable formulation, each of which is substantially, if not totally alcohol free. The formulations are also substantially free, if not totally free, of mono-, di-, and oligo-saccharides. An especially preferred embodiment is a ready-to-administer 1 mg/ml injectable dosage form having argatroban, lactobionic acid, and methionine.

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