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US Patent 7674906 Tetracyclic immunomodulatory compounds

Patent 7674906 was granted and assigned to Active Biotech AB on March, 2010 by the United States Patent and Trademark Office.

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Current Assignee
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Active Biotech AB
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
76749060
Patent Inventor Names
Lars Olof Göran Pettersson0
Muhammed Kamal Uddin0
Philip Huxley0
Chris James Brennan0
Dorthe da Graca Thrige0
Filippo Magaraci0
Ian Richard Matthews0
Date of Patent
March 9, 2010
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Patent Application Number
105375380
Date Filed
December 12, 2003
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Patent Primary Examiner
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Rita J Desai
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Patent abstract

The present invention relates to novel heterocyclic compounds, to methods for their preparation, to compositions containing them, and to methods and use for clinical treatment of medical conditions which may benefit from immunomodulation, including rheumatoid arthritis, multiple sclerosis, diabetes, asthma, transplantation, systemic lupus erythematosis and psoriasis. More particularly, the present invention relates to novel heterocyclic compounds, which are CD80 antagonists capable of inhibiting the interactions between CD80 and CD28.

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