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US Patent 7674791 Triazolopyrazines and methods of making and using the same

Patent 7674791 was granted and assigned to Biogen on March, 2010 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Current Assignee
Biogen
Biogen
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
76747910
Patent Inventor Names
Gang Yao0
Gnanasambandam Kumaravel0
Hairuo Peng0
Hexi Chang0
James E. Dowling0
Jeffrey Vessels0
Russell C. Petter0
Date of Patent
March 9, 2010
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Patent Application Number
105523050
Date Filed
April 9, 2004
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Patent Citations Received
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US Patent 11999740 Fused pyrazine derivatives as A2A / A2B inhibitors
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US Patent 11673894 Imidazopyrimidines and triazolopyrimidines as A2A / A2B inhibitors
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US Patent 11873304 Fused pyrimidine derivatives as A2A/A2B inhibitors
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US Patent 11884665 Pyrazolopyridines and triazolopyridines as A2A / A2B inhibitors
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Patent Primary Examiner
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James O. Wilson
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Patent abstract

The invention is based on the discovery that compounds of formula (I) possess unexpectedly high affinity for the A2a adenosine receptor, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including Parkinson's disease. In one embodiment, the invention features a compound of formula I (See formula on paper copy)

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