Patent 7659361 was granted and assigned to Nektar (pulminary therapeutics business unit) on February, 2010 by the United States Patent and Trademark Office.
The present invention is directed to maleamic acid derivatives of water soluble polymers, to chemically stable water-soluble polymer succinamic acid-active agent conjugates, and to methods for reproducibly preparing, characterizing and using such polymer reagents and their conjugates.