Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Hirohito Kita0
Jens Ponikau0
David Sherris0
Date of Patent
February 9, 2010
Patent Application Number
11897494
Date Filed
August 30, 2007
Patent Primary Examiner
Patent abstract
The present invention provides a method for identifying bacterial induced rhinosinusitis. The method comprises obtaining a nasal or paranasal mucus sample and detecting the presence of neutrophil degranulation in the mucus sample. Degranulation of neutrophils can be determined by morphological analysis of the cells in the mucus or by detection of released (i.e., “free”) granule content markers such as neutrophil elastase or myeloperoxidase. Based on an accurate determination of the cause of sinusitis as described herein, an appropriate treatment can be instituted.
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