Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Tina Myers Oakes0
Ella Sklan0
Jeffrey Glenn0
Kirk A. Staschke0
Date of Patent
February 2, 2010
Patent Application Number
11844993
Date Filed
August 24, 2007
Patent Primary Examiner
Patent abstract
The invention features methods and compositions for screening for agents that modulate replication of a virus, particularly Flaviviridae virus (particularly hepatitis C virus (HCV)), where the methods provide for detection of agents that modulate the binding of TBC and NS5A, the inhibition of TBC activity, inhibition of Rab1 activity, and/or the expression of the TBC protein and/or Rab1 protein. The invention also features methods of controlling viral replication, and agents useful in such methods.
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