US Patent 7645446 Glutamic acid decarboxylase (GAD) based delivery system
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Patent abstract
The invention provide methods and compositions for localized delivery of a vector comprising a therapeutic agent to a specific region of the brain that is overstimulated in neurodegenerative diseases. In particular, the invention provides methods and compositions used to deliver an adeno-associated virus vector (AAV) comprising a nucleotide sequence encoding glutamic acid decarboxylase (GAD) to cells in the subthalmic nucleus of the basal ganglia, mesaphilia and thalamus.
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Patent Inventor Names
Matthew During0
Michael Kaplitt0
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US Patent 07645446 Glutamic acid decarboxylase (GAD) based delivery system US Patent 7645446 Glutamic acid decarboxylase (GAD) based delivery system
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Patent Number
076454460
Patent Number
76454460
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Patent Jurisdiction
Patent Number
076454460
Date of Patent
January 12, 2010
0Patent Application Number
108024170
Date Filed
March 16, 2004
0Official Website
Patent Primary Examiner
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US Patent 07645446 Glutamic acid decarboxylase (GAD) based delivery system
Infobox
Is a
Patent jurisdiction
Patent number
07645446
Date of patent
January 12, 2010
Patent application number
10802417
Date Filed
March 16, 2004
Patent primary examiner
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