US Patent 7638322 Hypoxia inducible VEGF plasmid for ischemic disease

Patent 7638322 was granted and assigned to University of Utah on December, 2009 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

University of Utah

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

7638322

Date of Patent

December 29, 2009

Patent Application Number

10546115

Date Filed

February 23, 2004

Patent Primary Examiner

‌

Brian Whiteman

Patent abstract

Plasmids useful for treating ischemic disease, such as ischemic heart disease, are described. The plasmids express vascular endothelial growth factor (VEGF) under the control of a promoter (RTP801) that is up-regulated under hypoxic conditions. Pharmaceutical compositions for treating ischemic disease include mixtures of the hypoxia-regulated VEGF plasmids and pharmaceutically acceptable carriers. Methods for treating ischemic disease include administering such pharmaceutical compositions to a person in need of such treatment.