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Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Tsugunori Notomi0
Hidetoshi Kanda0
Kentaro Nagamine0
Toshihiro Yonekawa0
Date of Patent
December 29, 2009
0Patent Application Number
116157420
Date Filed
December 22, 2006
0Patent Primary Examiner
Patent abstract
The method of the present invention is based on a method wherein a nucleic acid is synthesized utilizing the hybridized 3′-end, which is synthesized by complementary strand synthesis, on a specific region of a target nucleotide sequence existing as the nucleotide sequence of the same strand as the origin for the next round of complementary strand synthesis. The hybridization to a specific region, which region is searched for mutations and polymorphisms, is repeatedly carried out according to the present invention. Thus, mutations and polymorphisms in a target nucleotide sequence are exactly copied to the reaction products.
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