A cable protection and guide device in which disengagement of a connection pin from a connecting pin hole is prevented. A cable protection and guide device in which a number of link frame bodies are flexibly and sequentially connected to each other such that a connecting pin of a preceding link plate is inserted into a connecting pin hole of the subsequent link plates. Cutout opening portions reside in the link plates. Connecting pins are inserted into the connecting pin hole 114. The connecting pins pass through a cutout portion of the side plate. Cutout opening portions in the link plates communicate with the connecting pin holes. A filling member integrally formed in the lid-shaped connecting arm seals against the connecting pin.