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US Patent 7608623 Hydroxyamidine and hydroxyguanidine compounds as urokinase inhibitors

Patent 7608623 was granted and assigned to WILEX on October, 2009 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee
‌
WILEX
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7608623
Date of Patent
October 27, 2009
Patent Application Number
11287480
Date Filed
November 28, 2005
Patent Primary Examiner
‌
James O. Wilson
Patent abstract

The present invention relates to novel compounds for inhibiting the urokinase plasminogen activator (uPA), which have high bioavailability and oral administerability, and also to the use thereof as therapeutic active compounds for the treatment of urokinase- or/and urokinase receptor-associated disorders such as, for example, tumors and metastasizing. The invention relates in particular to compounds containing hydroxyamidine or hydroxyguanidine groups.

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