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US Patent 7608594 Novobiocin analogues as anticancer agents

Patent 7608594 was granted and assigned to University of Kansas on October, 2009 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee

University of Kansas

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Brian S. Blagg0

Len Neckers0

Xiao Ming Yu0

Date of Patent

October 27, 2009

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Patent Application Number

112661490

Date Filed

November 3, 2005

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Patent Citations Received

US Patent 12024536 C-terminal HSP90 inhibitors

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US Patent 11708319 Biphenyl amides with modified ether groups as HSP90 inhibitors and HSP70 inducers

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US Patent 11939333 Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same

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US Patent 11944631 Combination therapies

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Patent Primary Examiner

Patrick T. Lewis

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Patent abstract

Novel analogues and derivatives of novobiocin are provided, including compounds having modifications to the amide side chain, coumarin ring, and sugar moieties. The compounds of the present invention are useful as heat shock protein 90 inhibitors, and may be used as anticancer and neuroprotective agents.

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