Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Ann E. Tollefson0
William S. M. Wold0
Konstantin Doronin0
Karoly Toth0
Date of Patent
October 27, 2009
Patent Application Number
11249873
Date Filed
October 13, 2005
Patent Primary Examiner
Patent abstract
Novel vectors which are replication competent in neoplastic cells and which overexpress an adenovirus death protein are disclosed. Some of the disclosed vectors are replication-restricted to neoplastic cells or to neoplastic alveolar type II cells. Compositions and methods for promoting the death of neoplastic cells using these replication-competent vectors are also disclosed.
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