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US Patent 7598335 Folate-receptor-targeting iron oxide nanoparticles coated with poly(ethylene glycol)

Patent 7598335 was granted and assigned to Kaohsiung Medical University on October, 2009 by the United States Patent and Trademark Office.

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Patent abstract

The present invention provides the synthetic method and superparamagnetic iron oxide nanoparticles capable of targeting to the folic acid receptors existing on the cell membranes and with high relaxivity. The iron oxide nanoparticles of the present invention can further be used as the contrast agents for magnetic resonance imaging (MRI).

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