Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Kirk Cryer0
Barton Holmquist0
Daniel Strydom0
Jin Seog Seo0
Date of Patent
September 22, 2009
0Patent Application Number
109978220
Date Filed
November 24, 2004
0Patent Primary Examiner
Patent abstract
The invention provides a palladium-promoted hydrolytic polypeptide cleavage process which selectively cleaves the polypeptide at a Cys-His cleavage site comprising solubilizing the polypeptide in a reaction mixture comprised of a palladium promoter dissolved in a high-concentration formic acid, wherein the concentration of the formic acid in the reaction mixture is between about 1 to about 22 molar.
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