US Patent 7589186 Isolated hOAT polynucleotide

Patent 7589186 was granted and assigned to Gilead Sciences on September, 2009 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Gilead Sciences

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

75891860

Patent Inventor Names

Tomas Cihlar0

Date of Patent

September 15, 2009

Patent Application Number

112325990

Date Filed

September 22, 2005

Patent Primary Examiner

‌

Manjunath N. Rao

Patent abstract

This invention is concerned with human organic anion transporter (“hOAT”). Isolated nucleic acid encoding hOAT is provided, along with isolated hOAT polypeptide. hOAT nucleic acid and/or hOAT polypeptide are employed in transgenic animals, recombinant cells, replicable vectors and analytical procedures for identifying hOAT agonists or antagonists, assays for identifying hOAT alleles and/or isotypes, screening tests for nephrotoxic or neurologically active compounds, and determination of drug-drug interactions within the kidney or brain.