Patent 7578173 was granted and assigned to Agilent Technologies on August, 2009 by the United States Patent and Trademark Office.
A variety of methods for operating a chromatography system are presented. Specifically, methods for operating a pumping system within a chromatography system are presented. The methods presented are directed to pumping apparatus in which very small amounts of fluid are pumped through the system. A number of techniques for detecting and compensating for leaks are presented as well as a number of techniques for operating the pumping system.