Patent 7557244 was granted and assigned to Ortho-McNeil Pharmaceutical on July, 2009 by the United States Patent and Trademark Office.
The present invention relates to compounds having the general Formula (I) with the definitions of X, Y, R1, R2, R3, R4, R9, and R10 given below, and/or a salt or ester thereof. Furthermore the invention relates to the use of said compounds for the treatment of Alzheimer's disease and their use for the modulation of γ-secretase activity.