Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Padma Marwah0
Ashok Marwah0
Henry A. Lardy0
Date of Patent
June 23, 2009
Patent Application Number
11862153
Date Filed
September 26, 2007
Patent Primary Examiner
Patent abstract
The instant invention provides potent antiandrogen compounds, such as 3β-acetoxyandrost-1,5-diene-17-ethylene ketal and 3β-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.
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