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US Patent 7550149 Attenuation of cytomegalovirus virulence

Patent 7550149 was granted and assigned to MedImmune, LLC on June, 2009 by the United States Patent and Trademark Office.

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Current Assignee
MedImmune, LLC
MedImmune, LLC
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
75501490
Patent Inventor Names
Richard Spaete0
George Kemble0
Gregory M. Duke0
Date of Patent
June 23, 2009
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Patent Application Number
116141410
Date Filed
December 21, 2006
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Patent Primary Examiner
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Stacy B. Chen
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Patent abstract

A method is provided for attenuating a cytomegalovirus comprising functionally disrupting an open reading frame of a Toledo genome region or its homolog and making chimeric CMV virus genomes.

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