The asynchronous sense amplifier for a ROM includes a current-mirror circuit, a first negative feedback inverter, a second negative feedback inverter, a first transistor group, a second transistor group and a feedback transistor. The feedback transistor connects the junction of the first transistor group and the first set of the current-mirror circuit and/or the junction of the second transistor group and the second set of the current-mirror circuit to ground, where the feedback transistor is controlled by the output of the first negative feedback inverter and/or the second negative feedback inverter, and the feedback transistor is smaller than one transistor of the second transistor group.