A nasal delivery device for and a method of delivering at least one substance to a nasal cavity of a subject. The nasal delivery device and method includes a delivery unit comprising: a nosepiece for fitting to a nostril of a subject; a mouthpiece through which the subject in use exhales; a breath analyzer for analyzing the concentration of at least one component in exhaled air from an exhalation breath; and a substance supply unit for supply at least one substance, the substance supply unit including a control unit for controlling the same to control supply of at least one substance in response to the detected concentration.