US Patent 7541453 siRNA targeting aquaporin 4

Patent 7541453 was granted and assigned to Dharmacon, Inc. on June, 2009 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Dharmacon, Inc.

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

7541453

Date of Patent

June 2, 2009

Patent Application Number

11598179

Date Filed

November 9, 2006

Patent Primary Examiner

‌

Brian Whiteman

Patent abstract

Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed.