Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yasuhiro Ishikawa0
Makoto Kigoshi0
Noboru Aoki0
Toshiro Ochiai0
Akihiro Uchida0
Eiji Hayakawa0
Kazuki Asanome0
Kazutoshi Kuroda0
Date of Patent
June 2, 2009
0Patent Application Number
105545110
Date Filed
May 7, 2004
0Patent Primary Examiner
Patent abstract
Microcrystals of (E)-8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione having an average particle size of less than 50 μm; microcrystals of (E)-8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione having an average particle size of less than 50 μm and a crystallinity of 20% or more or the like, which possess excellent solubility, stability, bioavailability, dispersing property in a pharmaceutical formulation; and the like are provided. A solid pharmaceutical formulation which is characterized by comprising the same is also provided.
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