US Patent 7538193 NO-modified hemoglobins and uses therefor

Patent 7538193 was granted and assigned to Duke University on May, 2009 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Duke University

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

75381930

Patent Inventor Names

Jonathan S. Stamler0

Date of Patent

May 26, 2009

Patent Application Number

117847800

Date Filed

April 9, 2007

Patent Primary Examiner

‌

David Lukton

Patent abstract

S-nitrosohemoglobin can liberate NO by transfer to a low molecular weight thiol in the circulatory system, allowing the delivery of NO to the tissues. The effect of administering isolated S-nitrosohemoglobin and low molecular weight thiol to a mammal is to increase delivery of oxygen and NO.