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US Patent 7531351 Liquid-gas-phase exposure reactor for cell culturing

Patent 7531351 was granted and assigned to ProBioGen AG on May, 2009 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
1

Patent attributes

Current Assignee
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ProBioGen AG
1
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
1
Patent Number
75313511
Patent Inventor Names
Uwe Marx1
Hikmat Bushnaq-Josting1
Marco Riedel1
Date of Patent
May 12, 2009
1
Patent Application Number
111513451
Date Filed
June 14, 2005
1
Patent Citations Received
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US Patent 11999929 Methods and systems for coating a cell growth surface
2
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US Patent 11685883 Methods and systems for coating a cell growth surface
3
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US Patent 11702634 Expanding cells in a bioreactor
4
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US Patent 11708554 Expanding cells in a bioreactor
5
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US Patent 11746319 Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
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US Patent 11773363 Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
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US Patent 11965175 Cell expansion
6
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US Patent 11667876 Expanding cells in a bioreactor
7
...
Patent Primary Examiner
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Walter D. Griffin
1
Patent abstract

Initiation of growth and cultivation of cells can be performed by introducing the cells into culture compartments of a liquid-gas-phase exposure bioreactor containing a supply chamber in which there are disposed hollow-filament membranes having an inside diameter of no larger than 5 mm, wherein an inner volume of said hollow-filament membranes forms the culture compartments. Approximately one half of the supply chamber is filled with a nutrient medium and a remainder is filled with a gas mixture. Perfusion of medium and gas is turned on simultaneously or separately. The hollow-filament membranes and the cells contained therein are cyclically exposed to the gas or liquid phase.

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