Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Smadar Cohen0
Inbar Freeman0
Date of Patent
April 14, 2009
Patent Application Number
11374279
Date Filed
October 11, 2005
Patent Primary Examiner
Patent abstract
The present invention provides bioconjugates comprising a sulfated polysaccharide such as alginate sulfate and hyaluronan sulfate and at least one bioactive polypeptide capable of binding a sulfate group of said sulfated polysaccharide. The bioactive polypeptide can be a heparin-binding polypeptide and/or a positively-charged polypeptide. Also, provided are delivery systems and methods for sustained release of said bioactive polypeptide(s) using said bioconjugates.
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