Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Bradley J. Martin0
Alastair Morgan Mackay0
Mark F. Pittenger0
Stephen L. Gordon0
Date of Patent
April 7, 2009
0Patent Application Number
106904350
Date Filed
October 21, 2003
0Patent Citations Received
0
...
Patent Primary Examiner
Patent abstract
Disclosed is a method for producing cardiomyocytes in vivo by administering to the heart of an individual a cardiomyocyte producing amount of mesenchymal stem cells. These cells can be administered as a liquid injectible or as a preparation of cells in a matrix which is or becomes solid or semi-solid. The cells can be genetically modified to enhance myocardial differentiation and integration. Also disclosed is a method for replacing cells ex vivo in a heart valve for implantation.
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