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US Patent 7501232 Method for cell selection

Patent 7501232 was granted and assigned to ProBioGen AG on March, 2009 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee
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ProBioGen AG
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
75012320
Patent Inventor Names
Uwe Marx0
Christian D. Demmler0
Christoph Giese0
Date of Patent
March 10, 2009
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Patent Application Number
108442520
Date Filed
May 12, 2004
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Patent Primary Examiner
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Gailene R. Gabel
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Patent abstract

The invention relates to a method for the non-invasive selection of single living cells under gentle conditions from mixtures of cells or cell cultures with respect to a specific production performance. To this end, the concentration of substances produced by the individual cells which become enriched at the cell membrane, such as reporter gene products (GFP) or specifically secreted products, such as antibodies, is determined by fluorescence-microscopic detection methods.

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