US Patent 7495098 Extraction of alkaloids from opium

Patent 7495098 was granted and assigned to Mallinckrodt (company) on February, 2009 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Mallinckrodt (company)

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

7495098

Date of Patent

February 24, 2009

Patent Application Number

11578627

Date Filed

May 6, 2005

Patent Primary Examiner

‌

Janet L. Andres

Patent abstract

A method for extracting at least one alkaloid from opium that includes dissolving opium in a solvent, heating the dissolved opium solution, cooling the dissolved opium solution, adjusting the pH of the dissolved opium solution with at least one first weak acid, filtering the dissolved opium solution to recover a filtrate; and then separating and purifying at least one alkaloid in the filtrate. Preferably, this includes an additional step of chilling the opium solution after adjusting the pH of the dissolved opium solution with at least one first acid. The preferred method for separating and purifying at least one alkaloid in the filtrate includes utilizing preparative liquid chromatography, however, solvent extraction and filtration can also be utilized.