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US Patent 7495098 Extraction of alkaloids from opium

Patent 7495098 was granted and assigned to Mallinckrodt (company) on February, 2009 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee
Mallinckrodt (company)
Mallinckrodt (company)
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7495098
Date of Patent
February 24, 2009
Patent Application Number
11578627
Date Filed
May 6, 2005
Patent Primary Examiner
‌
Janet L. Andres
Patent abstract

A method for extracting at least one alkaloid from opium that includes dissolving opium in a solvent, heating the dissolved opium solution, cooling the dissolved opium solution, adjusting the pH of the dissolved opium solution with at least one first weak acid, filtering the dissolved opium solution to recover a filtrate; and then separating and purifying at least one alkaloid in the filtrate. Preferably, this includes an additional step of chilling the opium solution after adjusting the pH of the dissolved opium solution with at least one first acid. The preferred method for separating and purifying at least one alkaloid in the filtrate includes utilizing preparative liquid chromatography, however, solvent extraction and filtration can also be utilized.

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