US Patent 7495079 Homogeneous preparations of IL-28 A

Patent 7495079 was granted and assigned to ZymoGenetics on February, 2009 by the United States Patent and Trademark Office.

Overview Structured Data Issues Contributors Activity

Is a

Patent

Patent attributes

Current Assignee

ZymoGenetics

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

74950790

Patent Inventor Names

Thomas R. Bukowski0

Kevin M. Klucher0

Lowell J. Brady0

Paul O. Sheppard0

Chung Chan0

Dennis L. Dong0

Hong Y. Liu0

Date of Patent

February 24, 2009

Patent Application Number

115497290

Date Filed

October 16, 2006

Patent Primary Examiner

‌

Elizabeth C. Kemmerrer

Patent abstract

Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.