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US Patent 7485726 Process for the preparation of risedronate sodium hemi-pentahydrate

Patent 7485726 was granted and assigned to Aurobindo Pharma on February, 2009 by the United States Patent and Trademark Office.

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Patent
Patent

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Current Assignee
Aurobindo Pharma
Aurobindo Pharma
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7485726
Patent Inventor Names
Ramesh Dandala0
Srinivasa Rao V. N Divvela0
Sivakumaran Meenakshisunderam0
Lenin Racha0
Date of Patent
February 3, 2009
Patent Application Number
11653556
Date Filed
January 16, 2007
Patent Primary Examiner
‌
Charanjit S. Aulakh
Patent abstract

The present invention relates to an improved process for the selective crystallization of 3-pyridyl-1-hydroxyethylidene-1,1-bisphosphonic acid sodium in pure hemi-pentahydrate form of Formula (I), by first converting 3-pyridyl-1-hydroxyethylidene-1,1-bisphosphonic acid into organic amine salt and then by replacing it with sodium salt.

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