Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Helen P. Findlay0
Fortunata McConkey0
Susan E. Hahn0
Lisa M. Cechetto0
Daad Sayegh0
David S. F. Young0
Date of Patent
February 3, 2009
0Patent Application Number
117094570
Date Filed
February 22, 2007
0Patent Primary Examiner
Patent abstract
The present invention relates to a method for producing cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, cytokines, interferons, target or reporter moieties and hematogenous cells.
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