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US Patent 7471394 Optical detection system with polarizing beamsplitter

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Patent
Patent

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7471394
Patent Inventor Names
Aravind Padmanabhan0
Bernard S. Fritz0
Date of Patent
December 30, 2008
Patent Application Number
11027134
Date Filed
December 30, 2004
Patent Citations Received
‌
US Patent 12025550 Fluidic cartridge for cytometry and additional analysis
0
‌
US Patent 11709116 Liquid flourescent dye concentrate for flow cytometry evaluation of virus-size particles and related products and methods
0
Patent Primary Examiner
‌
Tarifur Chowdhury
Patent abstract

An optical detection system for use in flow cytometry or the like, which includes a polarizing beamsplitter 820 such as a Wollaston prism. A light source provides an input light beam to a flow stream, wherein the input light beam has a polarization direction. The particles in the flow stream may produce an output light beam that includes a polarized component and a depolarized component. The polarizing beamsplitter receives the output light beam, and provides a polarized light beam and a depolarized light beam to a pair of detectors. The pair of detectors provide a first output signal that corresponds to the polarized light beam and a second output signal that corresponds to the depolarized light beam. A controller or processor may use the first output signal and the second output signal to help identify/classify particles and/or particle characteristics in the flow stream.

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