US Patent 7468361 2-ethyl and 2-ethylidene-19-nor-vitamin D compounds

Patent 7468361 was granted and assigned to Wisconsin Alumni Research Foundation on December, 2008 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Wisconsin Alumni Research Foundation

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

7468361

Date of Patent

December 23, 2008

Patent Application Number

11839586

Date Filed

August 16, 2007

Patent Primary Examiner

‌

Barbara P Badio

Patent abstract

Biologically active 19-nor vitamin D analogs substituted at C-2 in the A-ring with an ethylidene or an ethyl group. These compounds have preferential activity on mobilizing calcium from bone and either high or normal intestinal calcium transport activity which allows their in vivo administration for the treatment of metabolic bone diseases where bone loss is a major concern. These compounds are also characterized by high cell differentiation activity.