Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Ashok Marwah0
Henry A. Lardy0
Padma Marwah0
Date of Patent
December 9, 2008
0Patent Application Number
118375080
Date Filed
August 11, 2007
0Patent Primary Examiner
Patent abstract
The instant invention provides potent antiandrogen compounds, such as 3β-acetoxyandrost-1,5-diene-17-ethylene ketal and 3β-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.
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