Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
December 2, 2008
0Patent Application Number
111741860
Date Filed
July 1, 2005
0Patent Primary Examiner
Patent abstract
The invention provides a family of antibodies that specifically bind the human epithelial cell adhesion molecule. The antibodies comprise modified variable regions, more specially, modified framework regions, which reduce their immunogenicity when administered to a human. The antibodies, when coupled to the appropriate moiety, may be used in the diagnosis, prognosis and treatment of cancer.
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