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US Patent 7456180 Piperazine derivatives and their use as therapeutic agents

Patent 7456180 was granted and assigned to Xenon Pharmaceuticals on November, 2008 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Current Assignee
Xenon Pharmaceuticals
Xenon Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
74561800
Patent Inventor Names
Wenbao Li0
Shaoyi Sun0
Shifeng Liu0
Vishnumurthy Kodumuru0
Chi Tu0
Heinz W. Gschwend0
Mark W. Holladay0
Melwyn Abreo0
...
Date of Patent
November 25, 2008
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Patent Application Number
105670090
Date Filed
July 29, 2004
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Patent Primary Examiner
‌
Zachary C. Tucker
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Patent abstract

Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): where G, J, L, M, x, y, W, V, R2, R3, R4, R5, R6, R7, R8, R8a, R9, R9a, R10, R10a, R11 and R11a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.

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