US Patent 7446172 Cytokine protein family

Patent 7446172 was granted and assigned to ZymoGenetics on November, 2008 by the United States Patent and Trademark Office.

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Patent Inventor Names

Brian A. Fox0

David W. Taft0

Kevin M. Klucher0

Paul O. Sheppard0

Wayne Kindsvogel0

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Patent abstract

The present invention relates to polynucleotide and polypeptide molecules for zcyto20, zcyto21, zcyto22, zycto24, and zcyto25 proteins which are most closely related to interferon-α at the amino acid sequence level. The receptor for this protein family is a class II cytokine receptor. The present invention includes methods of reducing viral infections and increasing monocyte counts. The present invention also includes antibodies to the zcyto20 polypeptides, and methods of producing the polynucleotides and polypeptides.

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