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US Patent 7442159 Selection system

Patent 7442159 was granted and assigned to Domantis Limited on October, 2008 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Current Assignee
‌
Domantis Limited
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7442159
Date of Patent
October 28, 2008
Patent Application Number
09710444
Date Filed
November 10, 2000
Patent Citations Received
0
‌
US Patent 11884746 Matriptase and u-plasminogen activator substrates and other cleavable moieties and methods of use thereof
0
Patent Primary Examiner
‌
Jon D. Epperson
Patent abstract

The present invention concerns a method for the selection of a virus comprising the steps of: (a) providing a virus encoding and displaying a fusion polypeptide, said fusion polypeptide comprising a heterologous polypeptide inserted into the sequence of a viral coat protein polypeptide, wherein said virus comprises a cleavable site located within a displayed polypeptide; (b) exposing the virus to a cleaving agent; (c) propagating the virus comprising intact fusion protein.

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