Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Subhabrata Sen0
Wei Chen0
Andrew M. K. Pennell0
Daniel Joseph Dairaghi0
J. J. Kim Wright0
James B. Aggen0
Penglie Zhang0
Date of Patent
October 14, 2008
0Patent Application Number
112196370
Date Filed
September 1, 2005
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Compounds are provided that act as potent modulators of one or more of the CCR1, CCR2 and CCR3 receptors. The compounds are generally fused-, spiro- or bridged-nitrogen heterocycles having an aryl and heteroaryl component and are useful in pharmaceutical compositions, methods for the treatment of CCR1-, CCR2- and/or CCR3-mediated diseases, and as controls in assays for the identification of competitive receptor antagonists for the above chemokine receptors.
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