US Patent 7427627 N-(4-(4-methylthiazol-5-yl) pyrimidin-2-yl)-N-phenylamines as antiproliferative compounds

Patent 7427627 was granted and assigned to Cyclacel Limited on September, 2008 by the United States Patent and Trademark Office.

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Patent

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Current Assignee

Cyclacel

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

7427627

Date of Patent

September 23, 2008

Patent Application Number

11433312

Date Filed

May 11, 2006

Patent Primary Examiner

‌

Deepak Rao

Patent abstract

The present invention relates to 2-substituted 4-heteroaryl-pyrimidines, their preparation, pharmaceutical compositions containing them and their use as inhibitors of cyclin-dependent kinases (CDKs) and hence their use in the treatment of proliferative disorders such as cancer, leukaemia, psoriasis and the like.

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