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US Patent 7417109 Polymers for delivering nitric oxide in vivo

Patent 7417109 was granted and assigned to Duke University on August, 2008 by the United States Patent and Trademark Office.

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Is a

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Patent attributes

Current Assignee

Duke University

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Richard S. Stack0

Eric J. Toone0

Jonathan S. Stamler0

Date of Patent

August 26, 2008

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Patent Application Number

115001800

Date Filed

August 7, 2006

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Patent Citations Received

US Patent 12109365 Antimicrobial device comprising a cap with ring and insert

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US Patent 11944776 Peritoneal dialysis caps, systems and methods

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US Patent 11998715 Strip package for antiseptic cap

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US Patent 12076521 Antiseptic cap

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Patent Primary Examiner

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Patent abstract

Disclosed are novel polymers derivatized with at least one —NOx group per 1200 atomic mass unit of the polymer. X is one or two. In one embodiment, the polymer is an S-nitrosylated polymer and is prepared by reacting a polythiolated polymer with a nitrosylating agent under conditions suitable for nitrosylating free thiol groups. The polymers of the present invention can be used to coat medical devices to deliver nitric oxide in vivo to treatment sites.

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