Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Richard H. Bruce0
Alan G. Bell0
Eric Peeters0
Francisco E. Torres0
Date of Patent
August 26, 2008
0Patent Application Number
107199610
Date Filed
November 21, 2003
0Patent Primary Examiner
Patent abstract
A method is disclosed for high-throughput screening assay sample preparation and testing for the identification of binding between drug targets and library compounds, for use with a calorimetric device measuring the enthalpy of reaction for the binding. The method includes mixing a library compound with a specified solvent and mixing a target compound solution with a second specified solvent on a calorimetric device. The library compound/solvent is merged with the target compound/solvent solution and the library compound/solvent solution is also merged with a third solvent solution on the calorimetric device. The heats of reaction are detected for both merged solutions and are compared.
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