Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Mark Porter0
Michael Elashoff0
Arthur Castle0
Brandon Higgs0
Donna Mendrick0
Kory Johnson0
Date of Patent
August 19, 2008
Patent Application Number
10152319
Date Filed
May 22, 2002
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention is based on the elucidation of the global changes in gene expression and the identification of toxicity markers in tissues or cells exposed to a known renal toxin. The genes may be used as toxicity markers in drug screening and toxicity assays. The invention includes a database of genes characterized by toxin-induced differential expression that is designed for use with microarrays and other solid-phase probes.
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