Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
James W. West0
Julia E. Novak0
Scott R. Presnell0
Date of Patent
August 12, 2008
0Patent Application Number
115395540
Date Filed
October 6, 2006
0Patent Primary Examiner
Patent abstract
The polypeptides, and the polynucleotides encoding for them, described herein are IL-21 antagonists that bind with specificity and exhibit an EC50 that is not detectable in receptor binding studies. These molecules have mutations in the D helix of the IL-21 molecule, and can be used to inhibit the activity of IL-21 with its cognate receptor.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
