Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
July 22, 2008
0Patent Application Number
110935550
Date Filed
March 30, 2005
0Patent Citations Received
Patent Primary Examiner
Patent abstract
This document provides materials and methods related to PAPP-A polypeptides, aging, and transgenic non-human mammals whose genomes comprise a disrupted PAPP-A allele. Methods for making such transgenic non-human mammals, and using them and other mammals to identify and characterize agents that affect conditions related to PAPP-A activity, such as vascular restenosis, atherosclerosis, wound healing, cancer, fibrosis, bone development, fetal development, longevity, and fracture repair, also are provided.
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