US Patent 7402564 Synthetic peptide amides

Patent 7402564 was granted and assigned to Cara Therapeutics on July, 2008 by the United States Patent and Trademark Office.

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Patent Citations Received

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US Patent 11986509 Oligosaccharide formulations of kappa opioid receptor agonists

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US Patent 11865188 Gene therapy for AADC deficiency

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Patent Inventor Names

Claudio D. Schteingart0

Derek T. Chalmers0

Frédérique Menzaghi0

Guangcheng Jiang0

Javier Sueiras-Diaz0

Robert H. Spencer0

Roberta Vezza Alexander0

Zhiyong Luo0

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Patent abstract

The invention relates to synthetic peptide amide ligands of the kappa opioid receptor and particularly to agonists of the kappa opioid receptor that exhibit low P450 CYP inhibition and low penetration into the brain. The synthetic peptide amides of the invention conform to the structure of formula I:

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