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US Patent 7402131 Multiple laminar flow-based particle and cellular separation with laser steering

Patent 7402131 was granted and assigned to Arryx on July, 2008 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent
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Patent attributes

Current Assignee
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Arryx
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
74021310
Patent Inventor Names
Jessica Shireman0
Amy Anderson0
Daniel Mueth0
Joseph Plewa0
Lewis Gruber0
Neil Harris Rosenbaum0
Date of Patent
July 22, 2008
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Patent Application Number
115437730
Date Filed
October 6, 2006
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Patent Citations Received
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US Patent 11982611 Systems, apparatuses, and methods for cell sorting and flow cytometry
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US Patent 11978752 Aperture-metasurface and hybrid refractive-metasurface imaging systems
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US Patent 11873173 Multilayer hydrodynamic sheath flow structure
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US Patent 11906698 Broadband achromatic flat optical components by dispersion-engineered dielectric metasurfaces
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US Patent 11927769 Polarization sorting metasurface microlens array device
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US Patent 11988844 Transmissive metasurface lens integration
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Patent Primary Examiner
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Kiet T Nguyen
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Patent abstract

The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.

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