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US Patent 7384921 Polymorphic forms of 6-11 bicyclic ketolide derivatives

Patent 7384921 was granted and assigned to Enanta Pharmaceuticals on June, 2008 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee
Enanta Pharmaceuticals
Enanta Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
73849210
Patent Inventor Names
Zhe Wang0
Hui-Yin Li0
Yat Sun Or0
Yonghua Gai0
Datong Tang0
Guoyou Xu0
Date of Patent
June 10, 2008
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Patent Application Number
110574760
Date Filed
February 14, 2005
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Patent Primary Examiner
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Elli Peselev
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Patent abstract

The present invention includes EP-13420 polymorphic crystalline forms: Form I, Form II, Form Ia, and monohydrate and amorphous EP-13420 which posses distinct physical properties. In another embodiment of the present invention, there are provided methods of producing the various polymorphic forms in pure form or in combination with one another. The present invention also provides pharmaceutical compositions and formulations comprising the polymorphic and amorphous forms and methods of treating bacterial infections by administering the pharmaceutical compositions to a subject in need of such treatment.

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